One of the real problems with having a nice TV/Entertanment center is that every piece of equiptment has a seperate remote. All of these remotes say they are "Universal" and can control all your other devices but in my experience, these rarely work well if at all. But I found one that is really close to perfect.....
The Harmony Remote by Logitech works by a little different method than the others. It is a remote with a USB port that connects to your Mac. A website allows you to logon and identify all the components that you own by their model number. The it downloads and programs the remote to work correctly. And that it does. It controlls all of my components that us IR remotes. If it handled the one I have that is an RF remote, I would call it perfect.